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Filtered Search Results
Medchemexpress LLC FD-IN-1 | 1646682-14-5 | 98.6% | 50 MG
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FD-IN-1 is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM, central to the alternative complement pathway of the innate immune system. It also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5 μM, respectively. This compound demonstrates systemic suppression of AP activation in vivo and high oral bioavailability in mice (83%) and dogs (70%).
- Orally bioavailable and selective factor D inhibitor
- Inhibits factor XIa and Tryptase β2
- Systemic suppression of AP activation in vivo
- High oral bioavailability
- Suitable for research use only
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eMolecules 147702-14-5 | ChemScene | (S)-VANOL | 100mg | 536799514 | CS-0085175 | MFCD08459338 | 438.526 | C32H22O2
ChemScene | 1-(1H-Pyrazol-3-yl)ethanone | 1g | 569143898 | CS-0036771 | 20583-33-9 | MFCD07368316 | 110.116 | C5H6N2O
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Medchemexpress LLC (R)-pirtobrutinib | 2101700-14-3 | 99.8% | C22H21F4N5O3 | 10MG
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(R)-Pirtobrutinib is the R-enantiomer of pirtobrutinib (LOXO-305), a selective, non-covalent Bruton's tyrosine kinase (BTK) inhibitor used for biochemical and cellular research into BTK signaling and resistance mutations, including C481 substitutions. The compound is supplied as a high-purity solid with established solubility and storage profiles for laboratory use.
- High purity (99.8%).
- Selective, non-covalent BTK inhibitor active against C481 substitution mutations.
- Soluble in DMSO (≈200 mg/mL); ultrasonic assistance recommended.
- Light yellow to yellow solid appearance.
- Stable under defined storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Intended for research use only.
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eMolecules 69014-14-8 | Medchem Express | Tiotidine | 5mg | 495799471 | HY-101232 | 312.41 | C10H16N8S2
Medchem Express | Tiotidine | 5mg | 495799471 | HY-101232 | 69014-14-8 | 312.410 | C10H16N8S2
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eMolecules 1608-14-6 | Ambeed | N1N1N2N2-Tetramethyloxalamide | 1g | 686659927 | A1516734 | 144.174 | C6H12N2O2
Ambeed | 333-Trifluoropropan-1-ol | 5g | 552757613 | A803777 | 2240-88-2 | MFCD00190649 | 114.067 | C3H5F3O
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eMolecules 2921-14-4 | Aminooxyacetic acid hemihydrochloride | Ambeed | MFCD00012955 | 218.590 | C4H11ClN2O6 | 95.000 | Cl.NOCC(O)=O.NOCC(O)=O | 1g | 525234931
Aminooxyacetic acid hemihydrochloride | Ambeed | 2921-14-4 | MFCD00012955 | 218.590 | C4H11ClN2O6 | 95.000 | Cl.NOCC(O)=O.NOCC(O)=O | 1g | 525234931
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Medchemexpress LLC Acetic acid, 2-[[8-chloro-3-[(4-chlorophenyl)methyl]-4-(difluoromethoxy)-2-ethyl-5-quinolinyl... | 932708-14-0 | 99.4% | 456.27 | 50 MG
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Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2) with a Ki of less than 100 nM. It can be used in studies of asthma.
- Oral antagonist of DP2
- Ki < 100 nM
- Potential use in asthma studies
- For research use only
- Available in solid and solution forms
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Medchemexpress LLC 3-chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thi | 612542-14-0 | MFCD12032128 | 99.9% | 526.04 | C28H26ClF2N3OS | 25MG
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Hh-Ag1.5 (SAg1.5) is a potent small-molecule agonist of the Hedgehog signaling pathway that activates the Smoothened (Smo) receptor. It is supplied as a white to off-white solid with high reported purity and is used as a research tool to activate Hh signaling in cellular and in vivo studies. The compound is highly soluble in DMSO and has documented storage recommendations for powder and solutions.
- Potent Hedgehog pathway agonist with EC50 ≈ 1 nM.
- Activates Smoothened to induce downstream GLI transcription activity.
- High purity suitable for research (99.9%).
- Soluble in DMSO at 50 mg/mL; in vivo formulations achievable at ≥2.5 mg/mL.
- Stable as powder when stored cold; aliquot solutions to avoid freeze-thaw.
- Demonstrated biological activity in liver stem cell expansion at 5 μM in vitro.
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Strem, An Ascensus Company Buchwald PhosphorusLigand Kit
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CAS# . 1kit. Buchwald Biaryl Phosphine Ligand Master Kit for Aromatic Carbon-Heteroatom Bond Formation, Suzuki Coupling and Negishi Cross-coupling. . Molecular Weight: . Molecular Formula: . Color/form: Strem# 96-5500. http://www.strem.com/catalog/v/96-5500/
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Strem, An Ascensus Company BIS(2-DIPHENYLPHOSPHINOPHE-25G
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Bis(2-diphenylphosphinophenyl)ether, 98% DPEphos; Size: 25g; [166330-10-5]; (C6H5)2PC6H4OC6H4P(C6H5)2; Mol Wt:538.56; Color & Form: off-white pwdr.
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eMolecules 452967-14-5 | Medchem Express | IR415 | 5mg | 572596587 | HY-116999 | MFCD00238878 | 296.34 | C13H14F2N4S
Medchem Express | Pilaralisib analogue | 10mg | 446259874 | HY-11105 | 956958-53-5 | MFCD16621245 | 448.520 | C21H16N6O2S2
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STA PHARMACEUTICAL US LLC 2'-OTBS MeC(Bz) amidite | 1 g | CAS 160107-14-2 | InChIKey CSRPNZIUSKVNCV-YIZRFDMBSA-N
2'-OTBS MeC(Bz) amidite is a Amidite reagent (Subcategory: 2'-OH Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 160107-14-2
- MDL: No data
- InChIKey: CSRPNZIUSKVNCV-YIZRFDMBSA-N
- Molecular Weight: 978.211761998
- Molecular Formula: C53H68N5O9PSi
- Purity: ≥95%
- Container Type: 60 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 63 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@H](N2C(N=C(C(C)=C2)NC(C3=CC=CC=C3)=O)=O)O[C@@H]1COC(C4=CC=C(C=C4)OC)(C5=CC=C(C=C5)OC)C6=CC=CC=C6)O[Si](C)(C(C)(C)C)C)OCCC#N)C(C)C)C
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eMolecules 3563-14-2 | AstaTech | 4-OXO-4-((4-SULFAMOYLPHENYL)AMINO)BUTANOIC ACID | 0.25g | 718066435 | E78507 | 95 | MFCD00025390 | 272.28 | C10H12N2O5S
Ambeed | 2-(36-Dihydro-2H-thiopyran-4-yl)-4455-tetramethyl-132-dioxaborolane | 250mg | 572823196 | A102956 | 862129-81-5 | MFCD10700154 | 226.140 | C11H19BO2S
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Medchemexpress LLC Hh-Ag1.5 (SAg1.5) | 612542-14-0 | ≥98.0% | 526.04 | C28H26ClF2N3OS | 10MG
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Hh-Ag1.5 is a small-molecule agonist of the Hedgehog signaling pathway that activates Smoothened (Smo) and induces Gli-dependent transcription. It is used in vitro to stimulate Hh signaling, with reported activity at subnanomolar concentrations and documented application in reprogramming and expansion of quiescent liver stem cells.
- Potent Hedgehog pathway agonist with EC50 ≈ 1 nM.
- Selective Smoothened (Smo) receptor agonist with Ki ≈ 0.52 nM.
- Facilitates expansion of quiescent liver stem cells in vitro at 5 μM.
- High purity suitable for cellular assays (≥98% by HPLC).
- Molecular weight 526.04; formula C28H26ClF2N3OS; soluble in DMSO.
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Strem, An Ascensus Company CAS# 149646-83-3. 100mg. (+)-6,6'-{[(1R,3R)-1,3-Dimethyl-1,3-propanediyl]bis(oxy)}bis[4,8-bis(t-butyl)-2,10-dimethoxy-bibenzo[d,f][1,3,2]dioxaphosphepin], min. 95% (R,R)-Chiraphite. MFCD06798296
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CAS# 149646-83-3. 100mg. (+)-6,6'-{[(1R,3R)-1,3-Dimethyl-1,3-propanediyl]bis(oxy)}bis[4,8-bis(t-butyl)-2,10-dimethoxy-bibenzo[d,f][1,3,2]dioxaphosphepin], min. 95% (R,R)-Chiraphite. MFCD06798296. Molecular Weight: 876.99. Molecular Formula: C49H66O10P2. Color/form: off-white pwdr. Strem# 15-1455. http://www.strem.com/catalog/v/15-1455/
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